2-MDP

2-MDP
识别信息
	IUPAC命名法 3-amino-2-methyl-1,1-di(phenyl)propan-1-ol; ;
CAS号	14326-31-9 ; 14185-05-8
PubChem CID	26538;
ChemSpider	24719 ;
UNII	B6FTK35FGC; HCl: TJH732RKT9 ;
CompTox Dashboard (EPA)	DTXSID90912320 ;
化学信息
化学式	C16H19NO
摩尔质量	241.33 g·mol−1
3D模型（JSmol）	交互式图像;
	SMILES OC(c1ccccc1)(c2ccccc2)C(C)CN;
	InChI InChI=1S/C16H19NO/c1-13(12-17)16(18,14-8-4-2-5-9-14)15-10-6-3-7-11-15/h2-11,13,18H,12,17H2,1H3 ; Key:XGYCHIPEPHYUIH-UHFFFAOYSA-N ;

2-MDP也称为U-23807A是一种含氮有机化合物，分子式C
16H
19NO，为Upjohn研发的NMDA受体拮抗剂，在动物体内有苯环己哌啶（PCP）类似的功效，可作为解离剂和麻醉剂^[1]^[2]。

参考文献

^ Tang AH, Cangelosi AA, Code RA, Franklin SR. Phencyclidine-like behavioral effects of 2-methyl-3,3-diphenyl-3-propanolamine (2-MDP). Pharmacology, Biochemistry, and Behavior. February 1984, 20 (2): 209–213. PMID 6718449. S2CID 38908019. doi:10.1016/0091-3057(84)90244-2.
^ Blake JC, Davies SN, Church J, Martin D, Lodge D. 2-Methyl-3,3-diphenyl-3-propanolamine (2-MDP) selectively antagonises N-methyl-aspartate (NMA). Pharmacology, Biochemistry, and Behavior. January 1986, 24 (1): 23–25. PMID 3511477. S2CID 29762524. doi:10.1016/0091-3057(86)90038-9.
^ Moffett RB, Pickering TL. Central nervous system agents. 2. Synthesis of diphenyl primary and secondary aminopropanols. Journal of Medicinal Chemistry. November 1971, 14 (11): 1100–1106. PMID 5115211. doi:10.1021/jm00293a019.