JPC-211

JPC-211
臨床資料
给药途径	口服给药
ATC碼	未分配;
法律規範狀態
法律規範	Uncontrolled;
识别信息
	IUPAC命名法 5,6-dimethoxy-N,N-dipropyl-2,3-dihydro-1H-inden-2-amine; ;
CAS号	82668-33-5（; 83598-46-3 (maleate); 153570-58-2 (hydrochloride)）
PubChem CID	5626;
ChemSpider	5424;
UNII	929J96FO8T;
ChEMBL	ChEMBL16410;
CompTox Dashboard (EPA)	DTXSID50274471 ;
化学信息
化学式	C17H27NO2
摩尔质量	277.41 g·mol−1
3D模型（JSmol）	交互式图像;
	SMILES O(c1cc2c(cc1OC)CC(N(CCC)CCC)C2)C;

JPC-211（也称为PNU-99,194(A)或U-99,194(A)）是一种含氮有机化合物，分子式C
17H
27NO
2，为Upjohn研发的多巴胺受体拮抗剂。^[1]^[2]^[3]

参考文献

^ Claytor R, Lile JA, Nader MA. The effects of eticlopride and the selective D3-antagonist PNU 99194-A on food- and cocaine-maintained responding in rhesus monkeys. Pharmacology Biochemistry and Behavior. March 2006, 83 (3): 456–64. PMID 16631246. S2CID 39482275. doi:10.1016/j.pbb.2006.03.007.
^ Waters N, Svensson K, Haadsma-Svensson SR, Smith MW, Carlsson A. The dopamine D3-receptor: a postsynaptic receptor inhibitory on rat locomotor activity. Journal of Neural Transmission. General Section. 1993, 94 (1): 11–9. PMID 8129881. S2CID 32918280. doi:10.1007/bf01244979.
^ Kling-Petersen T, Ljung E, Svensson K. Effects on locomotor activity after local application of D3 preferring compounds in discrete areas of the rat brain. Journal of Neural Transmission. General Section. 1995, 102 (3): 209–20. PMID 8788069. S2CID 10327706. doi:10.1007/bf01281155.