跳至內容

JPC-211

維基百科,自由的百科全書
JPC-211
臨床資料
給藥途徑口服給藥
ATC碼
  • 未分配
法律規範狀態
法律規範
  • Uncontrolled
識別資訊
  • 5,6-dimethoxy-N,N-dipropyl-2,3-dihydro-1H-inden-2-amine
CAS號82668-33-5(
83598-46-3 (maleate)
153570-58-2 (hydrochloride))
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
化學資訊
化學式C17H27NO2
摩爾質量277.41 g·mol−1
3D模型(JSmol)
  • O(c1cc2c(cc1OC)CC(N(CCC)CCC)C2)C

JPC-211(也稱為PNU-99,194(A)或U-99,194(A))是一種含氮有機化合物,分子式C
17
H
27
NO
2
,為Upjohn研發的多巴胺受體拮抗劑。[1][2][3]

參考文獻

[編輯]
  1. ^ Claytor R, Lile JA, Nader MA. The effects of eticlopride and the selective D3-antagonist PNU 99194-A on food- and cocaine-maintained responding in rhesus monkeys. Pharmacology Biochemistry and Behavior. March 2006, 83 (3): 456–64. PMID 16631246. S2CID 39482275. doi:10.1016/j.pbb.2006.03.007. 
  2. ^ Waters N, Svensson K, Haadsma-Svensson SR, Smith MW, Carlsson A. The dopamine D3-receptor: a postsynaptic receptor inhibitory on rat locomotor activity. Journal of Neural Transmission. General Section. 1993, 94 (1): 11–9. PMID 8129881. S2CID 32918280. doi:10.1007/bf01244979. 
  3. ^ Kling-Petersen T, Ljung E, Svensson K. Effects on locomotor activity after local application of D3 preferring compounds in discrete areas of the rat brain. Journal of Neural Transmission. General Section. 1995, 102 (3): 209–20. PMID 8788069. S2CID 10327706. doi:10.1007/bf01281155.